European Journal of Biomedical and Pharmaceutical Sciences

INVESTIGATION OF ANTIMICROBIAL AND ANTIOXIDANT PROPERTIES OF NEWLY SYNTHESIZED SAMARIUM(III) COMPLEX WITH ?-HYDROXYKETONE AND 2,2?-BIPYRIDINE AS ANCILLARY LIGAND

Dr. P. Nandal, S. P. Khatkar, V. B. Taxak and R. Kumar*

ABSTRACT

New ternary Sm (III) complex, Sm (CHME) 3.bipy was synthesized by adopting solution precipitation method by employing β-hydroxyketone ligand 2-(4-chlorophenyl)-1-(2-hydroxy-4-methoxyphenyl) ethan-1-one (CHME) as main ligand and 2,2ʹ-bipyridine (bipy) as ancillary ligand. The structure of ligand and complex were confirmed by various techniques i.e. elemental analysis, FT-IR spectroscopy, 1H-NMR spectroscopy. The synthesized ligand and their corresponding complex were screened for their in vitro antimicrobial and antioxidant activities by tube dilution and DPPH method respectively. The complex was found to be promising candidate as new antimicrobial agent.

Keywords: Sm (III) complex, ?-hydroxyketone, 2,2?-bipyridine, Antimicrobial activity, Antioxidant activity.