Abstract
EVALUATION OF IN-VITRO ANTI-INFLAMMATORY ACTIVITY OF CORDIA MONOICA (ROXB.) LEAVES

Dr. A. Dhivya*, Dr. D. Jayasheela and Dr. R. Sivakumar

ABSTRACT

The present exploration was carried out to determine the in-vitro anti-inflammatory activity of Cordia monoica (Roxb.) leaves. Ethanol and Ethyl acetate extract of Cordia monoica leaves were taken for the study. The in-vitro anti-inflammatory assay was evaluated using protein denaturation assay and Proteinase inhibitory method. In both the methods, the ethanolic extract exhibited better activity than ethyl acetate when compared with standard (Aspirin). The extracts of Cordia monoica leaves showed dose dependent activity. The activity increased with increasing concentration. The phytochemical compounds such as phenol, tannin, flavanoid may be responsible for the anti-inflammatory activity. Thus it can be concluded that Cordia monoica leaves possess remarkable anti-inflammatory activity.

Keywords: Cordia monoica, IC50, protein denaturation, proteinase inhibition, Aspirin.


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