Abstract
SUSCEPTIBILITY PATTERN OF SECOND LINE ANTIBIOTIC COLISTIN AGAINST GRAM NEGATIVE BACTERIA CAUSING URINARY TRACT INFECTION IN SELECTED AREAS OF DHAKA CITY, BANGLADESH

Mohammad Asaduzzaman*, Kamalesh Baral, Md. Mafizul Islam, Md. Abu Nayem, Md. Jahangir Alam, Farha Matin Juliana, Nazmul Hossain, Biswajit Das, Runa Asma and Sumaiya Jannat Tapati

ABSTRACT

In a few decades, infections like Urinary Tract Infection (UTI) caused by multi-drug resistant (MDR) pathogens have become a serious problem, especially in the nosocomial setting. The emergence of multidrug-resistant Gram-negative bacteria that cause nosocomial infections is a growing problem worldwide. The World Health Organization (WHO) has identified antimicrobial resistance as one of the three most important problems for human health. We know that Colistin was first introduced in 1952 and was used until the early 1980s for the treatment of infections caused by gram-negative bacilli. Colistin has identified excellent activity against various gram-negative bacteria in vitro. Our aim was to assess the susceptible pattern of Colistin which also known as polymyxin E, is an antibiotic against gram negative bacteria causing Urinary Tract Infections. A total of 9178 urine samples were collected in 2016 (January-December) and out of which 837 (9.12%) were bacteriologically (Gram Negative Bacteria) positive. Male was found more prone to get UTI under 10 years and between 51-80 years of age and female was more affected in 10 to 50 years and over 80 years of age group. E. coli was the most prevalent (89.3%) isolate followed by Klebsiella spp. (7.5%), Pseudomonas spp. (2.3%) and Proteus spp. (0.9%). The most predominant sensitive organisms to Colistin were Klebsiella spp. (100%) in both male and female and resistant organisms Pseudomonas spp. (33.3%) and E.coli. (22.1%) in male and female found respectively.

Keywords: Colistin, Polymyxin, UTI, Gram negative bacteria, Resistance, Uropathogen.


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Tangudu Nagabhusana Rao

Download Article : Click here

News & Updation

  • NEW AUGUST ISSUE PUBLISHED

    AUGUST 2020 Issue has been successfully launched on 1 August 2020.

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 5.467 to 6.044, due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT