PRELIMINARY PHYTOCHEMICAL INVESTIGATION AND ANTIBACTERIAL EFFECTS OF LICHEN Parmotrema perlatum AGAINST HUMAN PATHOGENS
M.Revathy, S. Sathya shree, N. Manimekala, G. Annadurai* and M. Ahila
ABSTRACT
Lichens are familiar for their extraordinary secondary metabolites and Invitro efficacy of Parmotrema perlatum for their inhibitory activity against human pathogens Pseudomonas aeroginosa, Proteus vulgaris, Bacillus subtilis, Streptococcus pneumoniae, Streptococcus feacalis and Staphylococcus aureus were investigated by Kirby-bauer procedure of disc diffusion method. The maximum antibacterial activity was found to be 18 mm diameter of inhibition zone against Streptococcus pneumoniae followed by 16 mm diameter of inhibition zone against Staphylococcus aureus at the concentration of 75 and 100
l respectively. Phytochemical methods play an important position in investigating raw materials and properties for pharmaceutical industry and beneficial in establishing chemical ingredients that are basis of pharmacologically effective principles. Phytochemical investigation of ethanol and methanol extracts results in identification of Alkaloids, Phytosterols, Phenolic compounds and Tannins. Both the ethanol and methanol extracts of screened lichen were effective in inhibiting the growth of all the six multi resistant strains infecting human beings. FTIR results revealed the presence of potential functional group in Lichen Parmotrema perlatum. This current study recommended the opportunity of this lichen utilization in healing numerous diseases infected by these pathogenic microorganisms and related organisms.
Keywords: Parmotrema perlatum, Characterization Antimicrobial activity, Phytochemical investigation.
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