European Journal of Biomedical and Pharmaceutical Sciences

A TOW YEAR REVIEW ON THE BACTERIOLOGICAL PROFILE OF NEONATAL SEPSIS AT PRINCE RASHID BIN AL-HASSAN MILITARY HOSPITAL

Zuhair Nusair MD*, Ahmad Sharadgah MD, Zakaria Sharadgah MD and Osama Bataineh MD

ABSTRACT

Aim: To identify the bacteriological profile of neonatal sepsis in the neonatal intensive care unit at Prince Rashid Bin AL-Hassan Military Hospital. Material and Methods: All patients who were admitted to our unit from 1/1/2016 all through 31/12/2017 were included in our study. A blood culture specimen was taken for each of them to identify the bacterial isolates. Results: The total number of sample during the two year span of the study was 2120 newborns, 52.7% male and 47.3% female infants. The preterm neonates were 44.7% (n=948). The distribution according to the low birth weight was as follows LBW, VLBW and ELBW (31.2%, 7.2% and 2.6% respectively) (p=<0.001).The positive blood culture result was 12.5 %( n=266) of the total number of sample. We found that in the early onset sepsis cases the most common organisms were gram negative (62%) and also in the late onset sepsis cases (60.34%).The most frequent isolates were Escherichia coli (35.55%), Staphylococcus aureus (29.2%), Klebsiella pneumonia (15.7%), Coagulas Negative Staphylococcus epidermidis (CoNS) (6.05%) Conclusion: In conclusion, we achieved a worldwide advanced rank in terms of infection control, although we still need to work on gram negative sepsis prevention in both early and late onset sepsis.

Keywords: Neonatal sepsis, Gram negative, early onset, late onset, Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia, Coagulas Negative Staphylococcus epidermidis (CoNS).