European Journal of Biomedical and Pharmaceutical Sciences

EFFECT OF TWO DIFFERENT ASHMARIHARA FORMULATION IN THE MANAGEMENT OF ASHMARI-A PILOT STUDY.

Dr. Priyanka Chauhan*

ABSTRACT

Introduction: Urinary stone constitute one of the commonest diseases in our country and pain due to kidney stones is known as worse than that of labour pain. Among all the pain, abdominal pain always drags not only patient’s attention but also the curiosity of the surgeon. The information regarding Ashmari is available in almost all samhita (Ancient treatise) of Ayurveda. In India, approximately 5-7 million patients suffer from stone disease and at least 1/1000 of Indian population needs hospitalization due to kidney stone disease. Sushruta has mentioned conservative as well as surgicalmanagement for Ashmari. There are various form of medicines mentioned in the classics like Kwatha(decoction), Ghrita (ghee), Kshara (alkalipreparation), Vati (tablet), etc for management of Ashmari. Methodology: In this study, two doses forms of Ashamarihara formulation i.e. Kwatha and Ghanavati has been tried in the cases of urinary stone. Total 20 patients of Ashmari having different size of stones (from 3mm to 10mm) irrespective of the site were selected from OPD of Shalya Tantra, andallocated into two groups. In group-A (n=10) Ashmarihara Kwatha 40ml, two times a day for 30 days was prescribed. In group-B (n=10) Ashmarihara Ghanavati, 500mg two times a day for 30 days was prescribed. The assessment of relief in sign and symptoms was done after every 15 days for 1 month and further follow up was done for 1month after completion of treatment. Result: In patients of Group-A (Ashmarihara Kwatha) 4 stones were expelled out and 7 stones were decreased in their size. In patients of Group-B (Ashmarihara Ghanvati) 3 stones were expelled out and 10 were decreased in their size. This showed that Ashmarihara formulations have potential to disintegrate and expel out the stones form urinary system. Discussion: In modern science there are various surgical interventions like Dormia Basket, PCNL, ESWL etc. to remove the stone but they have their own limitations and there are chances of recurrence. Whereas, Ashmarihara formulations corrects Agniby Pachanaand Anulomanaproperties, so as to prevents formation of Aama and breaks the pathogenesis of Ashmari and in this way ithelps in prevention of further Ashmariformation. As per as the formulation is concern the patient preferred the Ghanavati as it is more palatable as compared to Kwathawith same result. Another issue is of preparation which is tedious job in this busy era. Conclusion: In this study, results were almost similarin both groups. So, it can be recommended that Ashmarihara Ghanavati is good option instead of Ashmarihara Kwatha, in the management of Ashmari.

Keywords: Ashmari, Urinary Stone, Urolithiasis, Ashmarihara Kwatha, Ashmarihara Ghanavati.