ASSOCIATION OF DIABETES MELLITUS TYPE II AND VON WILLEBRAND FACTOR LEVEL IN SUDAN
Mohamed Ahmed Ibrahim Konna and Mahdi H. A. Abdalla*
ABSTRACT
Background: Diabetes Mellitus is a metabolic disorder characterized by a higher incidence of thrombotic complications. Multiple causes have been proposed to explain the observed prothrombotic state. Objective: The purpose of this study was to determine Von Willebrand Factor level among diabetic type II Sudanese patients. Materials and Methods: eighty samples were included in this study (40 samples from diabetic type II patients and 40 samples from non-diabetic subject as controls. Random Blood glucose(RBG), HbA1C and Von Willebrand Factor level were determined. Results: means blood glucose level, HbA1C and VWF were significantly higher among diabetic patients than the control group. No significant differences were observed in the means of blood glucose level, HbA1C and VWF between males and females. Mean VWF level was significantly higher among uncontrolled D.M Type II Patients than Controlled D.M Type II Patients ( P.value:0.000). Conclusion: This study concluded that D.M Type II is associated with high VWF level. VWF was higher among uncontrolled D.M Type II Patients than controlled D.M Type II Patients.
Keywords: Diabetes Mellitus Type II, VonWillebrand Factor, Sudan.
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