NANOEMULSION: AN INNOVATIVE DRUG DELIVERY- A REVIEW
A. K. Vishwakarma*, P. D. Panda, N. K. Verma, D. K. Vishwakarma and J. N. Mishra
ABSTRACT
Nanoemulsion is kinetically stable and isotropic system of two immiscible liquids in sub micron size range. Nanoemulsions are composed of oil droplets dispersed in an aqueous medium and stabilized by surfactant molecules. Advantages of nanoemulsions include increased drug loading and enhanced bioavailability. The methods used for the production of nanoemulsions include HPH, microfluidization; ultrasonication and spontaneous emulsification Nanoemulsions have widespread applications in different fields such as pharmaceutics, food technology and cosmetics. This article mainly focuses on its application. In pharmaceutical observation, nanoemulsion is one of the chief dosage forms in delivering active ingredients to the objective area which has engrossed a great attention in recent years for its application in various fields. In the pharmaceutical field, nanoemulsions have been used as a drug delivery system through various systemic routes such as oral, topical and parenteral. Nanoemulsions are submicron sized emulsions which are used under high investigation as drug carriers for improving the delivery of therapeutic agents. The small droplets size 10-200 nm, high solubilization capacity, high interfacial area, low viscosity, transparent or translucent appearance, and high kinetic stability, make nanoemulsions used for various applications.
Keywords: Nanoemulsion, surfactant, emulsification, food technology and cosmetics.
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