LEVELS OF MINERALS AND ALBUMIN IN PRE AND POST HEMODIALYSIS PATIENTS
Miss. Juhi P. Sahajwani, *Dr. Nitin S. Nagane, Dr. Pratap E. Jagtap, Dr. Sushama P. Dhonde, Dr. Gajanan J. Belwalkar and Vaishali S. Bhandare
ABSTRACT
Background: Chronic kidney disease (CKD), featured by significant impairment of renal function, is a one of the major public health problems globally. Renal replacement therapies like dialysis and transplantation has increased the survival rate in CKD subjects worldwide. In past few years, the most preferable treatment for CKD patient is hemodialysis (HD). Aim and Objectives: The aim of this study is to estimate the clinical utility of minerals and albumin estimations in CKD patients underwent hemodialysis procedure. Martial and Methods: In this study, 50 chronic renal failure (CRF) patients receiving hemodialysis and 50 healthy controls of both the gender matching in age and sex were included. The patients were chosen on their estimated glomerular filtration rate (eGFR). The analysis of biochemical parameters like blood urea, serum creatinine, serum calcium, phosphorous, magnesium and albumin were estimated by autoanalyzer using kit reagents. Values were expressed as mg/dL. Results: In the present study posthemodialytic samples showed significantly high values of blood urea, serum creatinine, phosphorous and serum magnisium as compared to healthy controls but significantly lower than the pre haemodialysis samples. Mean values of serum calcium significantly reduced in posthemodialytic smaples as compared to controls but significantly higher as compared to prehaemodialysis. The mean values of serum albumin remains low as compared to prehaemodialysis and controls. Conclusion: In this study, serum minerals and albumin acting as a strong and independent predictor of overall mortality and cardiovascular outcome in CKD patients receiving haemodialysis treatment.
Keywords: Chronic kidney disease (CKD), Hemodialysis (HD), estimated glomerular filtration rate(eGFR), Cardiovascular disease.
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