European Journal of Biomedical and Pharmaceutical Sciences

ELECTROLYTE DISTURBANCE IN PATIENTS WITH ACUTE STROKE

Dr. Wissam F. Hassan*

ABSTRACT

Background: Stroke is the second most common cause of death after ischaemic heart disease and major cause of disability worldwide. electrolyte disturbances such as hyponatraemia, hypernatraemia resulting from inappropriate secretion of antidiuretic hormone (ADH), increase in Brain Natriuretic peptide (BNP) and Atrial Natriuretic peptide (ANP), 8 inappropriate fluid intake and loss; can lead to complications like seizures and death. Objectives: The purpose of the study was to evaluate the Electrolyte disturbance in patients with acute stroke. Patients and methods: The study was carried out in Neurology unit in the third floor of Baquba teaching hospital within one week of the onset of stroke. Performed on 50 patient randomly taking 35 male and 15 female they were diagnosed of having stroke clinically and by CT scan showing infarct or haemorrhage, The data obtained were; Age, sex, type of stroke, past medical history, drug history & Serum electrolytes level was estimated in all patients on admission. Association of electrolyte imbalance among acute stroke patients were identified and correlated. Analysis was carried out using simple statistical methods. This study conducted at 25\9 \2016 to 20\3 \2017. Results: All the patients were in between 40-80 years age. 70% of patients were males and 30% of patients were females. Majority of the patients (80%) had ischaemic stroke, (20%) patients had haemorrhagic stroke. Haemorrhagic stroke male, female patients; (57.1%;33.3%), (71.4%%,66.6%), (71.4%,66.6%) had no serum sodium, potassium neither chloride imbalances respectively. Of ischemic male, female patients; (50%,58.3%), (60.7%,14.6%), (82.1%,58.3%) had no serum sodium, potassium neither chloride imbalances respectively. Conclusions: This study reveals that electrolyte disturbances are quite common problem after acute stroke. Hyponatraemia and hypokalaemia are most common abnormalities in both ischaemic and haemorrhagic stroke patients.

Keywords: Ischaemic stroke, Haemorrhagic stroke, Hyponatraemia, Hypokalaemia.