European Journal of Biomedical and Pharmaceutical Sciences

A SYSTEMATIC OVERVIEW OF HAIR LOSS: DIAGNOSIS AND MANAGEMENT

R. Naveen Kumar Naik, Sk. Khaleel, Venkata Rohit Kumar.Chandolu*, J. N. Suresh Kumar

ABSTRACT

Hair loss (Alopecia) is one of the most common complaints among men and women of all ages and often significantly affects social and psychologicalwellbeing. Hair loss is usually associated with severe psychological disturbances, distress and symptoms of depression are commonly related to it and some other factors like Nutrition, infection, environment, auto-immune and congenital factors are all seen as possible triggers. Alopecia is usually treatableand self-limited, but it may be permanent in some cases. Hair loss may last over both short and long time span. A great number of examinations have to be done in order to confirm the Hair loss. The Diagnosis of hair loss is based on detailed clinical history, physical examination, clinical diagnostic tests,and laboratory testing and scalp biopsy. Careful diagnosis of the type of hair loss will aid in selecting effective treatment. The treatment of hair loss diseases is sometimes difficult because of insufficient efficacy and limited options. However, recent advances in understanding the pathophysiology and development of new remedies have improved the treatment of refractory hair loss conditions. Reassurance is an important component of any treatment regimen. Currently, treatment options for the hair loss disorder are extremely limited. The development of effective therapies for this form of intractable alopecia represents an important issue to be resolved. This article presents an overview of the most common clinical causes of hair loss and provides updated information on the current available therapeutic options of the disorders.

Keywords: Alopecia, androgenetic Alopecia (AGA), dihydrotestosterone (DHT).