A REVIEW : ANTIGOUT MEDICINAL PLANTS
Rohit R. Patil* and Gajanan S. Patil
ABSTRACT
It is a disorder of purine metabolism associated with increase level of serum uric acid (hyperuricaemia) above 6.8 mg/dl. Uric acid crystallizes in the form of monosodium urate and deposits in joints, tendons and in the surrounding tissues that manifested as a sudden burning pain, swelling, redness and tenderness in joints. Gout is the common cause of arthritis in men aged over the fifty. Incidence of gout in men is three to four times more common than women because before menopause, estrogen promotes urate wasting in the urine. The male to female ratio is 3.6: 1 but rare in pre-menopausal women and its incidence and prevalence increases with age. However, in patients over the age of 60, gout affects both men and women equally. The major objectives in gout management are to keep the serum uric acid level towards normal, prevent joint damage due to hyperuricemia and further occurrence as well as to promote the dissolution of existing uric acid crystals as well as prevent new crystal formation. However, the main reason for gout and hyperuricemia is related to the overproduction and hypo-excretion of renal uric acid. The aim of present review is to gather collective information of medicinal plants which are used in the therapeutic management of gout with respect to its parts used. This summerised information will be beneficial for further research.
Keywords: Uric acid, Hyperuricemia, Xanthine Oxidase Inhibitor, Gout, Medicinal Plants.
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