ANTIBACTERIAL PROPERTIES OF PEEL EXTRACTS OF PUNICA GRANATUM AND SOLANUM TUBEROSUM AGAINST HUMAN PATHOGENS
Vinitha Rani, Laveena K. B. Ramya and *Dr. Chandra M.
ABSTRACT
An attempt was made to screen the antibacterial activity of peel extracts of Punica granatum (Pomegranate) and Solanum tuberosum (Potato) against human pathogenic bacteria. Aqueous and ethanolic extract of two peels were prepared by hot extraction method. The antibacterial activity of peel extracts and standard antibiotic assay was evaluated against two bacterial pathogens viz., Escherichia coli and Staphylococcus aureus by Agar well diffusion method and concentration was 100 mg/10 μl. Distilled water and alcohol was used as negative and positive control. Standard antibiotic (Amphilox) was used for the assay. Minimum Inhibitory Concentration (MIC) was found out using Broth Dilution Method. The result of study showed the presence of wide spectrum of antibiotic activity against human pathogens. Alcoholic extract of pomegranate peel was found to be much efficient than the standard antibiotic used. Peel extracts showed the presence of essential phytochemicals such as alkaloids, flavonoids, steroids, terpenoids, tannin and saponin which are responsible for antibacterial activity.
Keywords: Antibacterial, Human pathogens, Punica granatum, Solanum tuberosum.
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