Abstract
CKAP4 PROTEIN MAY BE A NOVEL EARLY SERO-DIAGNOSTIC MARKER FOR LUNG CANCER

Dr. Warda Amin Shaikh, Dr. Tehmina Mussawir, *Dr. Syed Zawahir Hassan, Dr. Marium Naeem Billoo, Dr. Syeda Faryal Fatima, Dr. Duhaa Shahzad, Dr. Atiqa Bhali and Dr. Hidri Sinda

ABSTRACT

Lung cancer is the second most common cancer in both sexes. It is present in advanced stages hence has high mortality rates. Many patients when come for checkup in clinics are already in advanced stages of lung cancer. To improve prognosis it’s important to detect biomarkers involved in lung cancer. The most sensitive biomarker which has been seen in lung cancer is CKAP4 which was present in high level in patients than healthy individuals. The sensitivity of a diagnostic biomarker refers to the percentages of cases it manages to detect out of the total number of people who have the disease. CKAP4 has about 69% to 81% sensitivity in detecting lung cancer at lung cancer stage 1.

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