EVALUATION OF IN VITRO ANTIMICROBIAL ACTIVITY OF THAZHAMPOO MATHIRAI – A SIDDHA HERBO MINERAL FORMULATION
C. Mary Sharmila*, R. Chithra Devi, A. Sureka, N. J. Muthu Kumar and V. Banumathi
ABSTRACT
In the present scenario of increasing antibiotic drug resistance, and in the search of newer antimicrobial agents, Thazhampoo mathirai is a traditional siddha herbo mineral formulation in the siddha literature “siddha vaidhya thirattu” specifically indicated to treat nerikatti suram and the associated anda veekam (lymphadenitis and the associated scrotal swelling). The aim of the present study is to evaluate the antimicrobial activity of the siddha drug Thazhampoo mathirai. The antimicrobial activity evaluation was carried out by the cup plate method (Indian pharmacopoeia., 1996) against various strains of gram positive, gram negative bacteria and fungi. The test drug was diluted to various concentrations and the diameter of the zone of inhibition produced was measured against the standard ampicillin 10mg/ml. The obtained results reveal that the test drug produced a maximum zone of inhibition of 29 mm with Pseudomonas aeruginosa, 19 mm with salmonella typhimurium and candida albicans. we can conclude that the test drug possesses effective antimicrobial activity against gram positive, gram negative bacteria and fungal strain.
Keywords: Antimicrobial activity, Thazhampoo mathirai, Siddha, Herbo mineral drug.
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