Abstract
ESTIMATION OF OLMESARTAN MEDOXOMIL IN TABLET DOSAGE FORMS USING REVERSE PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY METHOD

*Divya Niranajan, Ankita Kishore, Rituparna Roy Sarkar, Praveen Tahilani, Gaurav Goyanar

ABSTRACT

Reversed phase high performance liquid chromatographic method was developed and validated for the estimation of Olmesartan medoxomil in bulk and formulation. Selected mobile phase was a combination of phosphate buffer with pH adjusted at 2.8 and acetonitrile (35:65% v/v) and wavelength selected was 250 nm. Retention time of Olmesartan medoxomil was 2.591 min. Linearity of the method was found to be 50-150 μg/ml, with the regression coefficient of 0.9993. Quantification was done by calculating area of the peak and the detection limit and quantitation limit ware 0.02μg/mL and 0.09μg/mL, respectively. There was no significant difference in the intraday and inter day analysis of Olmesartan medoxomil determined for three different concentrations using this method. Present method can be applied for the determination of Olmesartan medoxomil in quality control of formulation without interference of the excipients.

Keywords: Olmesartan medoxomil, Reverse phase, HPLC and Tablets.


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Dr. Dhrubo Jyoti Sen

Download Article : Click here

News & Updation

  • EJBPS: SEPTEMBER ISSUE PUBLISHED

    SEPTEMBER 2023 Issue has been successfully launched on 1 SEPTEMBER 2023.

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 5.467 to 6.044, due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT