European Journal of Biomedical and Pharmaceutical Sciences

SCREENING OF CLINICAL PRESENTATIONS AND COMPLICATIONS OF HYPOTHYROIDISM

N.Swathi*, M.Farjana*, V.Vijayakumar, M.Vishnuvardhan, M.Munendra, Dr.R.Vijaya kumar

ABSTRACT

Objective: Hypothyroidism has a broad clinical range of subclinical to severe diseases along with various complications, like Myxedema, Obesity, Birth defects, Mental Health Issues. The present study was aimed to evaluate the prevalence of hypothyroidism complications and its clinical presentations related to gender wise. Methods: The prospective study was conducted on 1000 subjects in Santhiram General Hospital during July 2017- Dec 2017. The subjects with (T3 = <80-220ng/dl), (T4 = <4.5–11.5μg/ dl) & (TSH = >5mIU/L) were selected. The data were analyzed using SPSS version 11.5, software and chi-square tests, p (<0.05) was considered significant. Results: Out of 304 patients, hypothyroidism complications were more prevalent in Obesity n= 125 (41.36%). In distribution of clinical presentation more prevalence was observed in weight gain n= 29(9.6%). Females (41.9%) were more prevalent than Males (36.4%) related to complications. Females (9.7%) were more prevalent than Males (9.1%), related to clinical presentations. Conclusion: Our study demonstrates that females are more prone to the complications and clinical presentations like Obesity and weight gain respectively. Hence it is necessary to measure the TSH levels in females.

Keywords: Prevalence, Hypothyroidism, Clinical Presentation.