Abstract
DRUG UTILISATION STUDY OF ANTI-EPILEPTIC DRUGS IN A TERTIARY CARE HOSPITAL

Dr. Manasi Limaye, Dr. Abhijeet V. Tilak, Dr. Mohanish Vaidya*, Dr. Sayan Das, Dr. Revati Kothari and Dr. S. A. Dabhade

ABSTRACT

Introduction: Epilepsy describes a condition in which a person has recurrent seizures due to a chronic, underlying process. 70 million people have epilepsy worldwide and nearly 90% of them are found in developing regions. Many patients have to be on treatment for a long period. Studies on antiepileptic drug utilization are important for the optimization of drug therapy and drug control. Aim: To study drug utilization pattern of antiepileptic drugs. Methods: This observational, cross-sectional study was conducted in Pune,India. Cases taking antiepileptic drugs for Epilepsy and seeking care in Dr. D.Y. Patil Hospital OPD and fulfilling the criteria were considered. Prescription of at least one Antiepileptic drug (AED) was the most important criteria. Evaluation was done on the basis of prescription data recorded. Results and Discussion: . Out of total 150 cases, in 48 cases (32%) single conventional AEDs was prescribed & in 10 cases (6.6%) single newer AEDs were prescribed. In 92 cases (61.3%) two or more AEDs were prescribed. Among total 293 prescribed AEDs, 214 prescription (73%) were conventional AEDs and 79 prescription (27%) were newer AEDs. The most commonly prescribed drug was Valproate (28.6%), followed by carbamazepine (23.8%) and phenytoin (18%). Among the newer AEDs prescription the commonest was levetiracetam (16.7%) followed by lamotrigine (7.8%). In GTCS the most common prescription was carbamazepine (45.3%) and Valproate (45.3%). Conclusion: Based on the findings of our study we conlude that polytherapy was commonly used in all types of epileptic seizures & the most commonly prescribed AED was sodium valproate, followed by carbamazepine, phenytoin and the new generation AED, Levetiracetam.

Keywords: Epilepsy, Drug Utilisation study, Prescription pattern, Monotherapy, Polytherapy, Antiepileptics, Phenytoin.


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Dr. Dhrubo Jyoti Sen

Download Article : Click here

News & Updation

  • EJBPS: FEBRUARY ISSUE PUBLISHED

    FEBRUARY 2023 Issue has been successfully launched on 1 FEBRUARY 2023.

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 5.467 to 6.044, due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT