Abstract
ANTIDIABETIC EFFECT OF ETHENOLIC EXTRACT OF ROOT OF ALSTONIA SCHOARIS LINN IN ALLOXAN INDUCED DIABETIC RAT

Radha Pal*, Kuldeep Singh, Raj K. Prasad and Manoj Mishra

ABSTRACT

Diabetes is very common disorder developd by harmonal imbalance of endocrine gland i.e islet of langrhance of pancrease in developed and developing countries, and the disease is sprading very rapidly in all over the world. Alstonia Scholaris is a plant of family apocynaceae and has a great medicinal value. From ancient time this plant is widely used by people to treat different type of diseases and ailments. This plant has been used in popular medicine for the treatment of the diabetes. it is native to the Indian subcontinent (especially in west Bengal, west-coast forests of south in india), Indomalaya, Malaysia and Australasia. Blood glucose level were increased significantly by using alloxan. Ethenolic root extract of plant was given to the diabetic rats in daily dose of 110mg\kg, 200 mg\kg body weight for 21 days. The significant alteration in fasting blood glucose level and body weight of diabetic rat were seen. So that the this study suggestd the potential effect of root in diabetes.

Keywords: Diabetes, Alstonia scholaris, Ailment.


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