European Journal of Biomedical and Pharmaceutical Sciences

HAEMATOLOGICAL AND BIOCHEMICAL CHANGES SEEN IN DENGUE FEVER IN A TERTIARY CARE HOSPITAL OF NORTHERN RAJASTHAN

Dr. Tarun Sharma, *Dr. Garima Gupta and Dr. A. R. Kalla

ABSTRACT

Introduction: Dengue is a viral infectious disorder, seen with high prevalence in developing countries. Despite multiple national level programmes to eradicate the disease still its incidence is not decreased as expected. Dengue presents with multiple sign and symptoms like fever, bodyache, tender hepatomegaly, rashes and many more, so it is associated with high morbidity and mortality. Objective: This study was conducted in Umaid hospital, Jodhpur (tertiary care hospital of child and maternal health) affiliated by Dr. S.N Medical College, Jodhpur. Main objective of the study is to evaluate the various haematological and biochemical changes seen in Dengue fever. Material and methods: It is a retrospective study. Haematological and biochemical datas of dengue patients were obtained from laboratory records. Results: In our lab we received total 4690 samples for dengue out of those 742(15.8%) were positive by rapid card test. NS1 Antigen was positive in 623(83.89%), IgG in 131(17.65%) and IgM in 14(1.86%). In hematology anemia was seen in 53% cases wile thrombocytopenia seen in 89% cases. Severe thrombocytopenia was predictor of poor prognosis. Conclusion: With help of haematological and biochemical changes we could assess the disease severity, prognosis of patients and recovery assessment.

Keywords: Dengue, haematological, biochemical, fever.