European Journal of Biomedical and Pharmaceutical Sciences

ASSOCIATION BETWEEN TORCH INFECTION AND DIFFERENT SOCIO-DEMOGRAPHIC FACTORS WITH RECURRENT MISCARRIAGE

Ali Hassan Mohammed*, Alaa Gasoob Abid and Zainab Khalifa Mohammed Ali

ABSTRACT

Miscarriages are the most common complication of pregnancy, affecting approximately 15% of all clinically recognized pregnancies in the general population. Recurrent miscarriage or recurrent pregnancy loss (RPL), defined as the loss of three or more consecutive pregnancies, affects 1% of couples trying to conceive. It has been estimated that 1–2% of second-trimester pregnancies miscarry before 24 weeks of gestation. The aim of this study is to found if there is any association between different socio-demographic factors, Toxoplasmosis, CMV, Rubella infections and recurrent miscarriage. This prospective case-control study was carried out in the private clinic between January 2016 and July 2016. Hundred, apparently healthy pregnant women with history of recurrent miscarriages with gestational age 10-20 weeks were selected as target group. Their ages ranged between 20 and 40 years. Every woman interviewed separately and asked number of questions designed in a questionnaire paper including full history, examination and information of different socio-demographic factors also blood sample were obtained from women for investigation to detect any infection with Toxoplasmosis, CMV, Rubella. Results showed the highest percent of recurrent miscarriage was occurred at the age group (21-30) years, (47%) also in the weeks of gestation < 10 weeks (78%). Nullipara, housewives, those lived in Urban region had higher percentage of recurrent pregnancy loss. (65%) of pregnant women with history of recurrent miscarriage completed her pregnancy while (35%) end with miscarriage, (99%) of woman with recurrent miscarriage who enrolled in this study not had any infection with Toxoplasmosis, CMV, or Rubella. It concluded that although the diagnosis of RPL can be quite devastating, it can be helpful for the physician and patient to keep in mind the relatively high likelihood that the next pregnancy will be successful.

Keywords: TORCH, Recurrent Misscarrage.