Abstract
EFFECT OF ORAL ADMINISTRATION OF FORSKOLIN, HOMOTAURINE, RUTIN, L-CARNOSINE, MAGNESIUM, VITAMINS B1, B2, B6 AND FOLIC ACID ON PATTERN-ELECTRORETINOGRAM AND VISUAL FIELD PARAMETERS IN GLAUCOMATOUS PATIENTS

*Italo Giuffre MD PhD

ABSTRACT

This is a review article about the potential neuroprotective activity of forskolin, a receptor-independent activator of adenylate-cyclase, associated to homotaurine, rutin, L-carnosine, vitamins B1, B2, B6, magnesium and folic acid in a food supplementation to patients affected by open angle glaucoma. The combined action on IOP and neuron survival suggests a neuroprotective activity of this food supplement in glaucomatous neurodegenerative disease, in which elevated IOP is the main risk factor, but not the only determinant of the progressive death of retinal ganglion cells from campimetric and electrophysiological points of view.

Keywords: Forskolin, glaucoma, IOP, neuroprotection.


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