Abstract
TRANS DERMAL DRUG DELIVERY USING POTENTIAL ETHOSOMES

G. Chinnadevi*

ABSTRACT

Ethosomes are vesicular carriers comprise of hydro alcoholic component and Phospholipids for enhanced drug delivery through skin. Drugs irritating gastrointestinal mucosa, drugs which are degradable in stomach, discomfortness with the parenteral method and first pass effect can be avoided using transdermal drug delivery with the help of Ethosomes vesicles. Ethosomes are soft, malleable, keeps the drug in shielded form and controlled release rate of drug over an extended period time. Cationic drugs such as propranolol, trihexaphenidyl, Cyclosporine, insulin, salbutamol, highly lipophilic drugs like cannabis, testosterone and minoxidil delivers bioactive molecules through the skin and cellular membranes in the form of vesicles.

Keywords: Ethosomes; vesicle; transdermal drug delivery; skin permeation.


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