Abstract
DIABETIC RETINOPATHY: AN OVERVIEW AND ROLE OF HERBAL PLANTS

*N. Jayasree, V. Jayasankar Reddy, V. Silvia Sudharshini, Dharani Prasad

ABSTRACT

The main objective of this review is detailed with the Diabetic retinopathy (DR) origin, complications, current treatment and their side effects and role of herbal plants in the treatment of Diabetic retinopathy. DR is the progressive disorder of chronic hyperglycemia. It is a leading cause of vision loss among working class. It is a multifactorial disease and some of them implicated in the pathogenesis of DR are Vascular endothelial growth factor (VEGF), Tumour necrosis factor- α (TNF-α), Interleukin-1β(IL-1β), Polyol pathway, oxidative stress, Protein kinase C-β(PKC-β).Photocoagulation, vitrectomy, anti VEGF agents and some anti inflammatory agents are currently in use. In this review, various molecular mechanisms, current treatment and their complications, importance of herbal plants in the treatment of DR have been discussed.

Keywords: Diabetic retinopathy, vascular endothelial growth factor, Fluorescein angiography, Optical coherence tomography, Laser treatment, vitrectomy, Anti-VEGF drugs.


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