European Journal of Biomedical and Pharmaceutical Sciences

PREVALENCE OF OBSTRUCTIVE SLEEP APNEA IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE IN INDIA

Dr. Deepak Kumar Shah, Dr. Navin Kumar Mishra*, Dr. Rishikesh Meena, Dr. Shivkumar K., Dr. Devendra P. Yadav, Dr. B. P. Verma and Dr. Malkesh Meena

ABSTRACT

Introduction: Chronic Obstructive Pulmonary Disease as well as Obstructive Sleep Apnea are two chronic, common respiratory diseases with significant morbidity and mortality; each having increased socio-economic burden; hampering the development of a nation independently. However, the concomitant occurrence of both known as “overlap syndrome” further complicates the scenario and makes it quite difficult to handle. At present, the prevalence of Overlap syndrome varies from 0.2%-28% globally. Data on overlap syndrome are sparse; perhaps because of failure to diagnose and report OSA on time. Aims and Objectives: In order to diagnose early a case of OSA among COPD patients and to find-out any correlation between Apnea –Hypopnea index (AHI) and Body Mass Index(BMI) with severity of COPD alone and Overlap syndrome in Indian population. Method and materials: We performed a cross sectional comparative study to evaluate OSA in diagnosed COPD patients who attended the outpatient department of our Hospital. All patients included in this study underwent evaluation of overnight polysomnography (cut off value of AHI for OSA was >5), ESS, mMRC scale, CAT score. Results: We evaluated 64 patients of COPD between 40 to 80 years of age group. Out of 64 patients, 11 (17.19%) had overlap syndrome with mean value of BMI 27.57 ± 3.54 (p=0.000), AHI 26.03 ± 6.41 (p<0.001), BPD 90.73±5.38 and nocturnal saturation 87.73 ± 1.95 (p=0.000). Conclusion: OSA was common among patients with COPD than general population with a prevalence of 17.19 in our study. The early recognition of co-existing OSA in COPD patients is of utmost clinically importance in the management of overlap syndrome and to decrease the burden of the fatal disease and to improve the quality of life. Patients with overlap syndrome have a greater risk of morbidity and mortality than either COPD or OSA alone.

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