European Journal of Biomedical and Pharmaceutical Sciences

GC-MS ANALYSIS OF BIOACTIVE COMPONENTS OF AGLAIA ELAEAGNOIDEA (JUSS.) BENTH.

S. Bangajavalli and *V. Ramasubramanian

ABSTRACT

Aglaia elaeagnoidea belongs to the family Meliaceae. It is commonly known as “Chokkala”. The present investigation was carried out to determine the possible bioactive components of bark and leaf of Aglaia elaeagnoidea using GC-MS analysis. While a – Caryophyllene (13.04%), 1- Heptatriacotanol (10.74%), 9,19-Cycloergost-24(28)-en-3-ol,4,14-dimethyl-, acetate,(3a,4a,5a)(9.25%),Cholestan-3-ol,2- methylene-, (3a,17a) (9.07%), Phytol (8.42%), 12-Oxabicyclo [ 9.1.0.]dodeca-3,7- diene,1,5,5,8-tetramethyl-, [IR-(IR*,3E,7E,11R*]- (5.54%) were found as the major compounds in the leaf of Aglaia elaeagnoidea, Squalene (16.56%), trans-Z-a-Bisabolene epoxide (13.50%), 7- Hexadecenal,(Z)(6.79%),Imidazole,2-amino-5-[(2-carboxy)vinyl] (6.56%), 8,11,14-Eicosatrienoic acid, (Z,Z,Z) (5.83%), were found as the major compounds in the bark of Aglaia elaeagnoidea . The presence of these constituents in the plant extract provides the scientific evidences for the antitumour, analgesic, antihypertensive and anti- inflammatory properties of plant.

Keywords: Aglaia elaeagnoidea, GC-MS, Caryophyllene, Phytol, Chokkala.