European Journal of Biomedical and Pharmaceutical Sciences

DRUG UTILIZATION STUDY, ADVERSE EFFECT AND ASSESSMENT OF QUALITY OF LIFE IN VITILIGO PATIENT IN DERMATOLOGY DEPARTMENT OF A TERTIARY CARE TEACHING HOSPITAL

*Dr. Shahenaz Malek and Dr. Bharti N. Karelia

ABSTRACT

Introduction: Vitiligo is a hypopigmentation disorder of skin where the loss of functioning melanocytes causes the appearance of white patches on the skin. Patients with vitiligo experience significant psychiatric morbidity. Depression, dysthymia, sleep disturbances, suicidal thoughts, suicidal attempts and anxiety have been found in those affected with vitiligo. Vitiligo can also lead to difficulties in forming relationships, avoidance of certain social situations, and difficulties in sexual relationship. Materials and methods: An observational, prospective study conducted in vitiligo patients at Tertiary care hospital. The study was conducted from January 2016 to April 2017. Patient’s Socio demographic data were recorded. Disease related history, medical history, drug history, history of allergy, family history, personal history details of co-morbid conditions, adverse drug reactions were noted and Quality of life index score was calculated. Result: Majority of the patients were 22.3% from 21-30 years of age group, female (64.7%), married (57.6%), housewife (37.1%), educated up to higher secondary level (54.7%) and had hypertension (5.2%) as most common co-morbid condition.95.2% of the patients had no family history of vitiligo.87.7% of the patients had personal habit of vegetarian diet. Majority of patients had vitiligo vulgaris (50.4%), stable (50.4%) and 70.9% of patients had vitiligo on exposed area of body. Conclusion: This study shows that over-all prescribing trends in our set-up require formation of guideline which leads to more appropriate and rational use of medications in vitiligo patients.

Keywords: Drug utilization study, Adverse effect, Vitiligo, Quality of life index.