Abstract
A CASE OF SERO-NEGATIVE SCLERODERMA WITH ILD

Anbarasan Thiru*, Pulkit Gupta, Mrityunjay Sharma, Bhupendra Kumar Rajak, Aarushi chokhani, Deepanjali Sharma, JK Mishra, Navin K. Mishra, Shivakumar K, Brighton M, Akilesh Tiwari

ABSTRACT

Systemic sclerosis is an uncommon connective tissue disorder characterized by multisystem involvement, heterogeneous clinical manifestations, a chronic and often progressive course, and significant disability and mortality.[1] It is diagnosed in the presence of characteristic clinical findings and is supported by specific auto antibodies in 90% of cases.[2] The lung is involved in the great majority of cases of scleroderma, with post-mortem series indicating a 70% to 100% incidence. Prior to the use of vasodilator therapy, the mean survival following a diagnosis of pulmonary hypertension was approximately 2 years.[3] Several case reports were published as Seronegative Scleroderma.[4] We report a case of systemic sclerosis who presented as interstitial lung disease where all specific auto antibodies were negative.

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