Abstract
A PROSPECTIVE STUDY ON CLINICAL PROFILE OF LOWER RESPIRATORY TRACT INFECTION IN A TERTIAERY CARE HOSPITAL.

Anagha Krishnadas*, Helan Theressa Antony, Shambhavi K., Eby Mathew, Hanumanthachar Joshi and Basavanna P. L.

ABSTRACT

Objective: To study the clinical profile of Lower respiratory tract infection (LRTI) and to identify the major risk factors, clinical manifestations and prescribing trends in LRTI. Methods: A prospective observational study was carried out for a period of 6 months in a tertiary care Hospital, Mysore . A total of 250 inpatients were included in the study on the basis of inclusion criteria. The data were collected by reviewing patients reports and was statistically analyzed using IBM SPSS Statistics software version 20.0. Result: Among 250 LRTI patients the incidence of COPD(45.2%) was found to higher than Pneumonia (30.4%) and PTB (24.4%). Fever, cough, breathlessness, chest pain, wheezing are the major clinical manifestations associated with LRTI .Smoking, alcoholism, age, gender, occupation, residential area were found to be the most common causes of LRTI. Commonly prescribed drug regimen for COPD and pneumonia are ceftriaxone (80%), Oxygen inhalation (54%), neb duolin+ budecort (85%), hydrocort (675), azithromycin (57%), PCT (44%), Syp. brozodex (31%), cefazone (18%), Tab. brophyle (15%). Prescribing trend for PTB includes CAT1(66%) Isoniazide, Rifampacin, Pyrazinamide and Ethambutol. CAT2 (34%) drugs are Isoniazide, Rifampacin, Pyrazinamide and Streptomycin. Conclusion: The study identified a number of potential risk factors that could be reduced through various interventions which eventually could reduce the incidence of LRTI.

Keywords: Intervention, prescribing trends, CAT1, CAT2,IBM SPSS.


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