European Journal of Biomedical and Pharmaceutical Sciences

SMALL CELL NEUROENDOCRINE CARCINOMA OF THE CERVIX IN A HIV POSITIVE PATIENT: A CASE REPORT

Manas Dubey*, Sonali Pandey, Sunder Singh and Vivek Kaushal

ABSTRACT

Background: Small cell neuroendocrine carcinoma of the cervix is a rare malignancy with an aggressive behavior, Histopathologically similar to small cell carcinoma of lung. Pelvic recurrence and distant metastasis are very common. In literature, the best treatment modality remains controversial. Case: From a case report in HIV positive patient and a literature review, we focus on prognostic factors and treatment of this cancer. Conclusion: Patients with small cell neuroendocrine cervical cancer have a poor prognosis. A multimodal treatment approach is required. Small cell carcinoma of the cervix is an aggressive tumor with a propensity for rapid recurrence; it is associated with high mortality.

Keywords: Uterine cervix, small cell carcinoma, neuroendocrine, HPV.