European Journal of Biomedical and Pharmaceutical Sciences

CHITOSAN THE JACK OF ALL TRADE FOR SUSTAINED RELEASE AN OVERVIEW

Prashant Kumar Sharma*, Ritesh Kumar Tiwari and Lalit Singh

ABSTRACT

Over the past few decades, tendency toward innovative drug delivery systems has majorly increased attempts to ensure efficacy, safety and patient acceptability. As discovery and development of new chemical agents is a complex, expensive and time-consuming process, so recent trends are shifting toward designing and developing innovative drug delivery systems for existing drugs. In those type of delivery polymer is needed for the stain drug deliver Chitosan the second most abundant next to cellulose, naturally occurring amino polysaccharide, derived as a deacetylated form of chitin. It isnon-toxic, biocompatible, antibacterial and biodegradable properties. As the chitosan is used as the polymer in the dosage form for the stain release of the drug in the systematic circulation. This review discusses the various forms of chitosan materials such as beads, films, microspheres, nanoparticles, nanofibers, hydrogels, etc. as drug delivery and the vast literature available on chitosan-based materials in drug delivery applications.

Keywords: Chitosan, Chitosan Beads, Chitosan Buccal Films, Chitosan Microspheres, Chitosan Nanoparticles, Chitosan Nanofibers, Chitosan Hydrogels.