European Journal of Biomedical and Pharmaceutical Sciences

TO STUDY THE CLINICAL PROFILE OF THE PATIENTS WITH OBSTRUCTIVE JAUNDICE

Dr. Chandranshu Tripathi*, Dr. Meenakshi Yeola (Pate) and Dr. Pankaj Gharde

ABSTRACT

Surgical Obstructive jaundice is most commonly encountered by general surgeons. This study focuses on early diagnostic measures for obstructive jaundice.To study the clinical profile of patients with obstructive jaundice.This study was carried out from October 2016 to September 2018 at AVBRH, Sawangi (Meghe), Wardha, Maharashtra, India. 35 pateints of obstructive jaundice were included in the study. Ethical Clearance was obtained from the institutional ethics committee. The demographic profile and etiology of all the patients affected with obstructive jaundice were recorded. The comparison and co relation between various diagnostic modalities: USG, CECT, MRCP were done keeping ERCP as a gold standard. The data was entered MS excel Spreadsheet and analysis was done using SPSS version 21.0.Out of 35 patients, the prevalence of SOJ was more common in 7th decade of life with male predominance. The total bilirubin level was more than 10mg% in malignant Obstructive jaundice. Pain in abdomen and jaundice were the most common presenting complaints. The benign cause of obstructive jaundice was present in 65.72% of the patients compared with malignant cause of obstructive jaundice (34.28%). In benign cases, the most common cause were choledocholithiasis and cholangiocarcinoma in malignant obstructive jaundice. The sensitivity of diagnosing benign cause of obstructive jaundice on USG, CECT and MRCP are 100%, 95.65%, 95.65% whereas malignant etiology are 66.67%, 83.33% and 100%.MRCP has got higher sensitivity in diagnosing benign and malignant cause of obstructive jaundice.

Keywords: Choledocholithiasis, ERCP, MRCP.