European Journal of Biomedical and Pharmaceutical Sciences

NEEDLE FREE INJECTION TECHNOLOGY

Balaji Reddy and Amera Begum*

ABSTRACT

The Needle-free injection (NFI) systems are novel ways to introduce various medicines Needle free injection technology was developed to reduce the number of needle stick accidents and associated problems. It is an extremely broad concept which includes a wide range of drug delivery systems that drive drugs through the skin which propels the drug through the skin, virtually nullifying the use of hypodermic needle. Needle-free technology offers very obvious benefit of reducing patient’s concern about the use of needle. Needle free injection gives effective injections for the wide range of drugs and bioequivalent to syringe and needle, results in less pain, and is strongly preferred by patients. This technology is not only thought to be beneficial for the pharma industry but developing world also and finds it highly useful in mass immunization programmes, bypassing the chances of needle stick injuries and avoiding other complications including those arising due to multiple use of single needle, also it has the added potential to increase compliance with dosage regimens and improved outcomes. Due to an ultrafine stream of high pressure fluid is created, that penetrates the skin devoid of the use of a needle, thus faster administration of drug occurs as compared to conventional needles. The main aim of modern needle-free drug delivery system is to enhance the prescribing and adoption of important drugs that require self-injection, such as biologics. Therefore, Needle free systems are designed to solve the problems created due to conventional needles making them safer, less expensive, and more suitable. In this review we aims to discuss about the needle less drug delivery system, their applications and advantages over needle injections. Today, they are many steadily developing technology that promises to make the administration of medicine more efficient and less painful.

Keywords: Needle Free Injection Technology, Powder, Liquid, Depot Injection, Injector, Components.