European Journal of Biomedical and Pharmaceutical Sciences

A REVIEW ON MODIFICATION OF NATURAL POLYMER

Nirju Rani Patar*, Mayuri Baruah, Koushik Sen Gupta, Biplab Kumar Dey

ABSTRACT

Polymers plays a vital role in each portion of lives. At present time every person depends on polymer to get various requirements. Different polymers are having different applications based on their sources. Newly, researches have been going on for the modification of natural polymer as they are easily available, non-toxic and economical nature. So they are mostly used over the synthetic polymer though we can use both of them in the Pharmaceutical field. However, it is not compulsory that all the polymers we had till now from various sources should possess all its desired properties, there might be some particular properties which can be absent in the polymers we have till now. There are some drawbacks like poor bioavailability, short half-lives, physical and chemical instability, in Pharmaceutical dosage forms. Modification of the intrinsic properties of the natural polymers can provide enhanced stability, drug release pattern and many other characteristics which are lacking in natural polymer. For these reasons development of polymer grafting is initiated. Advancement in polymer science is essential as they can improve the range of application. Polymer grafting is one of the most propitious technique for the modification of natural polymer properties and loss in the original characteristics is very less.

Keywords: Polymer, natural polymer, synthetic polymer, pharmaceutical field, bioavailability, polymer science, polymer grafting.