European Journal of Biomedical and Pharmaceutical Sciences

TRANSDERMAL DRUG DELIVERY: A NOVEL APPROACH TO DRUG DELIVERY

Neetu Bishnoi*, Praveen Tahilani and Dr. Jitendra Banweer

ABSTRACT

The skin has attracted much attention as an alternative route for administering systemically active drugs. The potential advantages associated with transdermal drug delivery are well documented. Transdermal therapeutic system are defined as self contained, discrete dosage forms which, when applied to the intact skin, delivery the drug through the skin, at controlled rate to the systemic circulation. Thus, it is anticipated that transdermal drug delivery system (TDDS) can be designed to maintain suitable plasma drug level for therapeutic efficacy by using skin as the port of entry of drugs. The goal of pharmaceutical research is to find drugs with desirable therapeutic and low risk of undesirable side effects. Recent research and development efforts have been channelized into the development of drug delivery system for controlled drug administration through various routes (or parts) of administration, for example, the skin, to maximize the bioavailability, to optimize the therapeutic efficacy, and/or minimize the side effects of the drug.

Keywords: Transdermal Drug Delivery System, Novel drug Delivery System, Skin, Bioavailability.