European Journal of Biomedical and Pharmaceutical Sciences

RECENT UPDATE ON BOTANICALS FOR TREATMENT OF DIABETIC NEPHROPATHY

Shweta Sehrawat* and Himesh Soni

ABSTRACT

Diabetic nephropathy is a major cause of end-stage renal disease, and there has been a continuous increase in its incidence worldwide in the past two decades. Diabetic nephropathy is characterized by microalbuminuria, renal and glomerular hypertrophy, mesangial expansion with glomerular basement membrane thickening, arteriolar hyalinosis, and global glomerular sclerosis, which ultimately cause the progression of proteinuria and renal failure. This article represents detail survey of the 20 plants and synthetic antioxidant used for Diabetic Nephropathy. The literature shows that there are more than 400 plant species showing anti-diabetic activity. In the indigenous Indian system of medicine, many plant species remain to be scientifically established especially those with reno-protective effects. It was found that all the plant parts or extracts used in Diabetic Nephropathy. The detailed study is needed to explore the ethno-botanical uses of medicinal plants and further clinical experimentation is also needed to scientifically evaluate these widely used herbal remedies for possible bioactive effects.

Keywords: Traditional uses, Diabetic Nephropathy(DN) & Medicinal plants.