DIVERSE CONNOTATIONS - GUISE OF CELLS IN PLEURAL FLUID CYTOLOGY INTERPRETATION FOR PERSONIFICATION PERSE OF ACCURATE DIAGNOSIS
*Dr. (Major) Ragini Thapa and Dr. Shreesha Khandige
ABSTRACT
Background: Non-malignant and malignant causes of effusion can be ascertained comparatively by non-invasive technique of interpretation of pleural fluid cytology. With this basis the present study on cytology of pleural fluids was chosen to be studied. The diagnostic efficacy and accuracy of the cytologic study of the fluid is ascertained to the fact that the cell population present in the sediment is a bigger picture of a much larger surface area than that obtained by needle biopsy. Materials and Methods: One hundred and twenty (120) samples of pleural fluid were examined for total cell count, cell type and cellular features along with fluid biochemistry from Oct 2014 to Oct 2016. Results: A total of 80% samples were exudative and 20% were transudative. Total leukocyte count (TLC) was less than1000 cells/cu.mm in most (85.89%) of transudative effusions. Overall 50.44% of exudative effusions had TLC greater than 1000 cells/cu.mm. It was noted that 99.88% of tuberculous effusions had more than 50% lymphocytes, 77.25% had protein greater than 5 gm/dl and 89.63% had glucose greater than 60 mg/dl. Approximately 18% of pleural effusions were positive for malignant cells. The primary site could be assessed by pleural fluid cytology in many case scenarios. Conclusions: The most useful test in establishing the diagnosis of pleural effusion is pleural fluid cytology and pleural fluid cell count. Cytologic study of pleural fluid is a complete diagnostic modality which aims at pointing out the etiology of effusion as well as, in certain cases, a means of prognostication of disease process.
Keywords: Effusion; pleural fluid, exudate, malignant effusion.
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