European Journal of Biomedical and Pharmaceutical Sciences

STUDY ON INTRAVITREAL AVASTIN(BEVACIZUMAB) IN BRVO WITH MACULAR EDEMA

Dr. Mohd. Ayaz Bhat*, Dr. Waseem Raja and Dr. Rafia

ABSTRACT

Purpose: To evaluate efficacy and safety of intravitreal injections of bevacizumab(avastin) in the treatment of macular edema due to branch retinal vein occlusion (BRVO). Methods: Retrospective, consecutive case series. Study was done on 52 eyes of 52 patients. Outcome measures include: Best corrected visual acuity (BCVA), central macular thickness (CMT) by spectral domain optical coherence tomography, and complications. Results: BCVA improved by a mean of 3.2 lines from an initial mean BCVA: 0.1 (counting fingers: 1 m-0.3) to a mean BCVA 0.4 (0.05-0.8) over the follow-up period of 6.9 months (4-12 months). CMT was reduced from an initial mean of 613 (401-959 μ) to the mean of 400 μ (274-623 μ) at the end of the follow-up period. This was achieved through a mean number of injections: Four with a range (3-6 injections). Conclusion: IVB is an effective treatment for ME secondary to BRVO. There was a significant improvement of VA and significant reduction in macular thickness in many cases, but not in all cases.

Keywords: .