ANALGESIC AND ANTI-INFLAMMATORY ACTIVITY IN SIDDHA DRUG FORMULATION KAALAKODI RASAM
Dr. S. Thanikaiselvi* and Dr. R. Antony Duraichi
ABSTRACT
Siddha system is the ancient system of heeling and it's based on combination of medical practices and preventive methods, as well as alchemy and mysticism. Herbo metallic preparations play an important role in traditional system of medicine. One such effective & safe herbo metallic formulation is kaalakodi rasam (KKR). As indicated in Siddha literature KKR is a herbo metallic formulation treated for osteoarthritis. Aim: To study of analgesic and anti-inflammatory activity in the siddha drug formulation Kaalakodi rasam. Materials and methods: The analgesic and anti-inflammation activities evaluation were done by Acetic acid Induced Writhing Test method in Swiss albino mice and Carrageenan induced acute hind paw oedema method on Wister albino rats, respectively. Doses of different proportions 100mg, 200mg of KKR powder suspension were given to the animals for a stipulated period of time. Results and conclusion: KKR having significant analgesic activity against the acetic acid-induced writhing in mice and anti-inflammatory activity against the carrageenan -induced paw oedema in rats.
Keywords: Kaalakodi rasam, analgesic and anti-inflammatory study, siddha, osteoarthritis.
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