European Journal of Biomedical and Pharmaceutical Sciences

PHYTOCHEMICAL AND IMMUNOMODULATORY SCREENING OF PHYSALIN B, ISOLATED FROM METHANOLIC EXTRACT OF UNRIPE FRUITS OF PHYSALIS MINIMA

K. Sunitha* and M. Nagulu

ABSTRACT

Phytochemicals are chemicals of plant origin. Phytochemicals are chemicals produced by plants through primary or secondary metabolism. Phytochemicals generally are regarded as research compounds rather than essential nutrients because proof of their possible health effects has not been established yet. Immunology is one of the most rapidly developing areas of medical biotechnology research. All drugs which modify immune response generally categorized as immunomodulators. In the present study, Phytochemical screening included extraction, isolation and identification bioactive compounds of methanolic extract of unripe fruits of Physalis minima by different analytical methods. The isolated compound was found to be Physalin B in comparison to the previous published data and it was screened for immunomodulatory activity. So it has been concluded that the methanolic extract of unripe fruits of Physalis minima possess a steroidal alkaloid, an active constituent Physalin B, which may be used to treat different ailments.

Keywords: Phytochemical, Physalis minima, Physalin B, Immunomodulator.