Abstract
A COMPARATIVE STUDY TO EVALUATE THE EFFECT OF HEMODIALYSIS ON MAXIMUM CORRECTED QT INTERVAL (QTCMAX) AND QT DISPERSION IN CHRONIC KIDNEY DISEASE

Praveenkumar I. Kusubi, Dr. Niranjan M.* and Dr. Shiddalingesh Salimath

ABSTRACT

Sudden cardiac death is common in patients on hemodialysis, and may occur in the immediate postdialysis period, when ventricular premature complexes are common. Elevated QT dispersion is associated with increased risk of ventricular arrhythmias following myocardial infarction, but has not previously been assessed in patients with chronic renal failure. We studied electrocardiograms recorded in 50 patients before and after a single hemodialysis session between February 2018 and July 2018. QT dispersion was prolonged in patients before hemodialysis (63.1 6 20.6 ms) and significantly increased after hemodialysis to levels comparable to those seen following myocardial infarction (76.6 6 27.0 ms; P, 0.01). Because QT dispersion reflects nonhomogeneous recovery of ventricular excitability, hemodialysis patients may be at significantly greater risk of reentrant arrhythmias and sudden death in the postdialysis period.

Keywords: Hemodialysis, QT interval, QT dispersion, chronic renal failure.


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