Abstract
A STUDY OF CLINICAL PATTERN OF ANTIBIOTICS INDUCED ADVERSE CUTANEOUS DRUG REACTIONS IN A TERTIARY CARE HOSPITAL

Dr. Vimmi Agrawal*, Dr. S. P. Pandey, Dr. Usha Gupta

ABSTRACT

Abstract: Adverse cutaneous drug reactions (ACDRs) are caused by a wide variety of agents. Antibiotics are one of the commonest drug groups to cause ACDRs and clinical pattern of cutaneous ADR changing every year. Aims: Our objective was to evaluate clinical pattern of adverse cutaneous drug reactions of antibiotics in a tertiary care hospital. Methods: fifty five patients with adverse cutaneous drug reactions were recruited for this study during 2013-2014. Results: The Most of ACDRs belonged to the age group of 21-30 years (36.36%) with male predominance. The most common eruptions observed were maculopapular rash (36.36%) followed by fixed drug eruption (27.27%), SJS/TEN (18.18%) and Erythema multiforme (9.09%). Conclusion: The pattern of ACDRs And the drugs causing them is remarkably different in our population. Knowledge of these drug eruptions, the causative drugs and the prognostic indicators is essential for the clinician.

Keywords: Cutaneous drug reactions, antibiotics.


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