PHARMACOGNOSTICAL AND PHARMACEUTICAL EVALUATION OF SHUNTHYADI EYE DROPS
Dr. Chandan Sharma, Dr. Sarika Makwana, Dr. D. B. Vaghela, Dr. Harisha C. R. and Dr. V. J. Shukla
ABSTRACT
Background: Shunthyadi eye drops contain drugs like cow Ghrita, Shunthi (Zingiber officinale), Saindhava Lavana (rock salt), which are claimed to be effective in Shushkakshipaka (Dry eye). In present study, it has been used as topical eye drop in Dry Eye. Objective: Present study is aimed to look out on herbal drugs used in the preparation of Shunthyadi eye drops and standardization of Pharmacognostical, Physicochemical parameters and HPTLC evaluation. Methods: Identification and Authentication of raw drug Shunthi was done by pharmacognostical study i.e. morphological features, organoleptic characters and powder microscopy. Physicochemical evaluation and HPTLC was carried out of final product. Results: Pharmacognostical Study of raw drug Shunthi showed presence of Scalariform vessels, Oleo resin content, Annular vessels, Simple starch grains of Shunthi etc. Pharmaceutical evaluation showed results Specific Gravity 0.89, Refractive Index 1.47, Acid Value 1.94, Saponification Value 220, Iodine Value 11.98, pH 6.00, Loss on drying 0.1, High Performance Thin Layer Chromatography results was found at 254 nm and 366 nm in to 6 and 5 spots respectively in before spray. Conclusion: Identification, authentication of herbal drug used in the preparation of Shunthyadi eye drops has been done. Physicochemical evaluation has been carried out of prepared drug which is further useful for standardization of Shunthyadi eye drops and clinical researches.
Keywords: Dry Eye, Pharmcognosy, Shunthyadi eye drop, Shushkakshipaka, Pharmaceutical.
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