Abstract
TAMARIND PULP EXTRACT MEDIATED RECOVERY OF FLUORIDE INDUCED REPRODUCTIVE TOXICITY ON MALE ALBINO RAT.

Shyamal Kanti Das, Soumendra Nath Karmakar* and Anindita Dutta

ABSTRACT

The present study was under taken to evaluate the possible protective action of the tamarind pulp extract on sodium fluoride (NaF) mediated reproductive toxicity on albino Wistar rat (male). In present study, different experimental animal groups were treated with NaF (2mg/ml/100gm), both NaF (2mg/ml/100gm) and tamarind pulp extract (1mg/100gm body weight) along with control group animals treated with water respectively. NaF treatment caused drastic reduction in physiological, biochemical and reproductive parameters in comparison with control group of animals. Body weight along with testicular and epididymal weight have been increased after co administration of tamarind pulp extract in comparison with their respective NaF treated group. In the same manner, recovery has taken place in serum protein, serum glucose, sperm count, sperm motility and serum testosterone concentration after tamarind pulp extract co supplementation with NaF. Histological structure has also been improved after tamarind pulp extract administration. It can be concluded that tamarind pulp extract has potency as protective agent against NaF induced reproductive toxicity on albino rats.

Keywords: Sodium fluoride, tamarind pulp, sperm count, sperm motility, histology.


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