Abstract
THE DYNAMICS OF CHANGES IN THE KINETICS OF LIPID PEROXIDATION IN RAT BRAIN MITOCHONDRIA IN DIFFERENT AGES AND VEGETABLE PREPARATIONS' EFFECT ON THIS PARAMETER

Dalimova Surayo Nugmanovna, Kuziev Sherali Nasrullaevich*, Levickaya Yuliya Vladimirovna, Umarova Gulbakhor Bazarbaevna, Mukhamadjanova Gozal Mukhamadjanovna and Nasriddinov Khusan Ziyoyiddin o’g’li

ABSTRACT

In the process of aging of organisms, lipid peroxidation is activated in cellular mitochondria. Activation of lipid peroxidation is shown in the accumulation of malondialdehyde in the mitochondria. This process has been studied on the mitochondria of the liver and brain cells. In the present time investigated number of natural antioxidants, which reduce the concentration of oxidants. In this paper, the property supramolecular complex of antioxidant PRE-1 studied on MDA in vitro and in vivo conditions. This compound shows antioxidant property in different age categories rat's mitochondria and reduces the concentration of MDA.

Keywords: aging, antioxidant, malondialdehyde – MDA, lipid peroxidation, supramolecular complex.


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