Abstract
GREEN SYNTHESIS OF ZnO NANOPARTICLES USING LEAVES EXTRACT CASSIA FISTULA AND DOPED WITH COPPER (Cu: ZnO NPs) TO ENHANCE THE ACTIVITY OF ANTIBIOTICS AGAINST STAPHYLOCOCCUS AUREUS

Atul K. Wanjari* and Gopal M. Shende

ABSTRACT

In the present study green synthesis of ZnO nanoparticles (70 nm) carried out from leaves of Cassia fistula and doped with copper (Cu:ZnO NPs). These Cu:ZnO NPs further used to study the effect on antibacterial activity of different antibiotics by disk diffusion method. Staphylococcus Aureus was used as the test strain. The combination of antibiotics with Cu:ZnO NPs increases there activity against Staphylococcus Aureus. Surface modified copper doped Cu:ZnO NPs have significantly enhance the activity of antibiotics. The Cu:ZnO NPs was quite stable at different temperature. According to the SEM image the nanoparticles synthesized have different size and heterogeneous morphology.

Keywords: Copper doped zinc oxide nanoparticles, Green Synthesis, Antibacterial properties, Staphylococcus Aureus, Cassia Fistula.


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