European Journal of Biomedical and Pharmaceutical Sciences

GLYCATED HEMOGLOBIN AND SERUM LIPID PROFILE IN TYPE 2 DIABETES MELLITUS

*Dr. Sundara Veena Nethala, Dr. Bhagyalakshmi Vanapalli

ABSTRACT

Introduction: The chronic complications of Diabetes Mellitus (DM) affect many organ systems and are responsible for the majority of morbidity and mortality associated with the disease. They have several lipid abnormalities including elevated plasma triglycerides (TG), elevated Low Density Lipoprotein-Cholesterol (LDL-C) and decreased High Density Lipoprotein-Cholesterol (HDL-C), Very Low Density Lipoprotein (VLDL). The main aim of study is to know the prevalence of HbA1c and Serum lipid profiles in Type 2 DM. Materials and Methods: This is a prospective randomized study conducted from February 2009 to June 2009. Serum lipid profile and HbA1c are estimated in Type 2 DM patients and compared those with normal subjects. Results: Total cholesterol, Triglycerides, Low density lipid were higher than normal subjects, which are mainly responsible for cardiovascular diseases in Type 2 diabetics. HbA1c was higher in males than in females, which also shows more percentage in diabetics when compared with normal subjects. Conclusion: There was no major difference in the glycemic status of males and females as measured by Fasting glucose levels. HbA1c can be used as an indicator of glycemic control as well as a predictor of lipidemic state in type 2 diabetics.

Keywords: Type 2 Diabetes Mellitus, HbA1c, Triglycerides, Low Density Lipoprotein, Very Low Density Lipoprotein, High Density Lipoprotein.