European Journal of Biomedical and Pharmaceutical Sciences

PREVALENCE OF HELICOBACTER PYLORI IN PATIENTS WITH DYSPEPSIA UNDERGOING UPPER G.I ENDOSCOPY

Waseem Raja*, Rohey jan, Zarka Masoodi, Rouf H Beigh, Ajaz ahmad and Dr. Majeed

ABSTRACT

Introduction: Dyspepsia is a common clinical condition encountered in day to day practice and accounts for 60% of patient referrals to gastroenterology clinics and endoscopy plays a major role in the management. The prevalence of H. pylori infection is reported to be more than 50% worldwide. Objective: The objective of the present study was to study the prevalence of H. pylori in patients with dyspepsia undergoing upper G. I. endoscopy. Material & Methods: A prospective Cross sectional study was conducted in Gastroenterology Division at District Hospital Budgam over a period of Fifteen months from March 2018 – June 2019. 100 cases of dyspepsia who fulfilled inclusion criteria were enrolled in the study and were subjected to upper GI endoscopy with antral biopsies after taking informed written consent from patients. Biopsy specimens were subjected to Rapid Urea Kit test (RUT) and histopathology. RUT Positive for H Pylori was indicated by colour change of the medium from yellow to pink. Results: Out of 100 patients, 34 patients were Helicobacter pylori positive {RUT + = 34 patients}, with overall prevalence of 34%. The Prevalence was higher in the age group of 40-59 years (58.8 %), with Male Prepondance, (70.5%) were Males compared to Females (29.4%). Most predominant symptom in H Pylori positive patients were Post-prandial fullness (47%), followed by Epigastric pain (29.4%). According to endoscopic finding, Out of 34 H Pylori positive cases, Gastric Ulcer was seen in (15) patients, followed by Duodenal ulcer (12) and Gastritis in (7) patients. H Pylori was more common among Smokers (70.5%) & in residents of Rural population (88.2 %). Conclusions: In this study, we concluded that Helicobacter pylori were consistently associated with peptic ulcer disease. In depth studies are needed to determine associated factors of H pylori infection in this region.

Keywords: Dyspepsia, Upper G.I Endoscopy, H Pylori, Rapid Urea Test.