European Journal of Biomedical and Pharmaceutical Sciences

LIPID PROFILE IN TYPE 2 DIABETES MELLITUS

Faraz Farishta* and Rahul Reddy

ABSTRACT

The serum lipid profile of 50 type2 diabetes mellitus patients was studied and compared with age and sex matched non diabetic healthy controls. The serum lipid levels were correlated with various clinical profiles of diabetes like sex, duration, severity of diabetes. In the present study group, the average duration of diabetes was 8 years. of 50 patients 82% were males and 18% were females. The average duration of diabetes was 8 years. 24 patients were on oral hypoglycemic drugs, 16 were taking both oral hypoglycemic and insulin, 10 were on only insulin. Among the complications, diabetic retinopathy was commonest complication52%, second commonest was neuropathy 40%. Ishemic heart disease was seen in 28%, nephropathy was seen in 18%, cerebro vascular accident in 14%. The mean values of the entire lipid fraction TG, TC, LDLc, VLDLc, were statistically significantly higher in diabetes than healthy controls. There was correlation between lipid levels and duration of diabetes for all lipid fractions which were significant. All lipid fractions showed a progressive increase severity of diabetes. The difference was statistically significant. Degree of control diabetes was inadequate as more than 50% had high glycosylated haemoglobin. This probably the main reason for significant Dyslipidemia and as well as complication.

Keywords: Ishemic heart, TG, TC, LDLc, VLDLc.