Dr. Talla Vinay Bhushanam*, M.S. M.Ch., Dr. Alugolu Rajesh, M.S., M.Ch., Dr. Megha Shantveer Uppin M.D., Dr. Suryaprabha M.D., D.M.


Plasma cell granuloma (PCG)/ inflammatory pseudo- tumour or inflammatory myofibroblastic tumour is relatively rare entity arising within numerous organs. PCGs have been found in many organ systems however, involvement of brain that too primary is very rare with upto 28 cases reported till date in English literature. A 19 year male patient suffering from secondary generalised seizures, diagnosed imageologically as tuberculoma failed to show clinical and radiological improvement despite adequate anti-tubercular treatment, was subjected to surgical excision with intraoperative corticography. We herein describe our case along with the review of literature regarding primary CNS plasma cell granulomas. Radiological diagnosis of granulomas, treated empirically as tuberculosis needs to be followed cautiously and the diagnosis reviewed in case if there is no response to chemotherapy and be subjected to biopsy/excision and histopathology/culture for there are many radiological mimics with intracranial plasma cell granuloma being one among them.

Keywords: Central nervous system, inflammatory, intracranial, myofibroblastic tumour, plasma cell granuloma, pseudo-tumour.

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